Houston, TX, USA | M.D. Anderson Cancer Center
Industry:Healthcare - Hospitals
Job Description:84 people have viewed this job
Independently design, execute and interpret in vitro and in vivo experiments to validate targets, optimize compound selection and explore therapeutic potential of drug targets.
Manage sample collection, biomarker analysis and data analysis of clinical specimens derived from human clinical trials conducted within the Integrative Medicine Program or other departments/programs at the institution.
Develop extensive knowledge and experience in key areas of tumor biology including, but not limited to oncogenic signaling, tumor microenvironment, cancer stem cell, EMT, epigenetic deregulation or apoptosis and immune cell profiling. Design and develop cell and molecular biology assays to define mechanism of action of compounds of interest. Identify pharmacodynamics of natural product of interests to be used in pre-clinical and clinical evaluations.
Conduct in vivo antitumor efficacy or chemopreventive study using human tumor mouse xenograft, subcutaneous and orthotopic models as well as genetically engineered mouse models.
Independently perform data analysis and properly interpret results. Analyze data generated by various studies and leverage results for the design of future studies.Effectively present results and conclusions to the PI and other collaborators.
Assist PI on their scientific endower including leading natural product discovery effort (experiment design and following up the progress of projects), writing and editing manuscripts, abstracts for scientific meetings, protocols (animal and laboratory), reports and grant proposal.
Work closely with and instruct students, postdoc and other new laboratory personnel with respect to proper laboratory techniques, the use of laboratory equipment, and safety procedures to enhance research efforts and obtain desired results.
Education Required: PhD in one of the natural sciences or related field or Medical degree With PhD, no experience required.
Experience Required: With Medical degree, two years of experience in experimental or scientific work.
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