Sr Research Associate, T Cell Engineering
Emeryville, CA, USA | Leading Pharmaceutical / Biotech Company
Industry:Pharmaceutical / Biotech
Job Description:53 people have viewed this job
We are seeking an experienced, creative and motivated Research Associate /Senior Research Associate to join our growing team in Emeryville.In this role, you will contribute to the company’s efforts to develop next-generation cell therapies in solid tumor malignancies.Specifically, you will be part of a cell biology research team focused on engineering approaches to enhance CAR T anti-tumor activity.
The successful candidate will have a strong immunology background and will be expected to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.
RESPONSIBILITIES (include, but are not limited to):
Employ viral and non-viral based strategies for the genetic modification of T cells with chimeric antigen receptors (CARs).
Culture and characterize CAR T cells
Plan and execute in vitro functional assays with human T cells according to project timelines and goals
Assist with design of murine models/experiments to evaluate CAR T cell function in vivo.
Maintain up-to-date knowledge of immunotherapy field
Coordinate tasks across projects, demonstrating prioritization and planning
Effectively communicate plans and results in both oral and written form
Ability to work in a highly dynamic collaborative team environment
Other duties as assigned
QUALIFICATIONS AND EXPERIENCE
BS or MS degree in immunology/cell biology
0 – 5+ years of experience in the immunology/immunotherapy field (immunotherapy background strongly preferred)
Excellent mammalian cell culture and sterile technique required
Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo) required
Experience with immune cell-based assays including cytotoxicity assays, cell proliferation assays and ELISAs
Experience with viral and/or non-viral gene delivery
Proficiency in Excel, PowerPoint, Prism, and other programs to create and distribute reports
Excellent problem-solving and time management skills
Strong organizational and record keeping skills
Self-motivated and willing to accept temporary responsibilities outside of job description
Comfortable in a fast-paced company and able to adjust workload based upon changing priorities
Excellent interpersonal, verbal and written communication skills with the ability to interact with individuals from a variety of levels and functions