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Sr Research Associate, T Cell Engineering

Emeryville, CA, USA | Leading Pharmaceutical / Biotech Company

  • Industry:
    Pharmaceutical / Biotech
  • Position Type:
    Full-Time
  • Functions:
    Biotech/R&D/Science
  • Experience:
    3-5 years
Job Description:
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Job Description


We are seeking an experienced, creative and motivated Research Associate /Senior Research Associate to join our growing team in Emeryville.In this role, you will contribute to the company’s efforts to develop next-generation cell therapies in solid tumor malignancies.Specifically, you will be part of a cell biology research team focused on engineering approaches to enhance CAR T anti-tumor activity.


The successful candidate will have a strong immunology background and will be expected to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.


RESPONSIBILITIES (include, but are not limited to):


Employ viral and non-viral based strategies for the genetic modification of T cells with chimeric antigen receptors (CARs).

Culture and characterize CAR T cells

Plan and execute in vitro functional assays with human T cells according to project timelines and goals

Assist with design of murine models/experiments to evaluate CAR T cell function in vivo.

Maintain up-to-date knowledge of immunotherapy field

Coordinate tasks across projects, demonstrating prioritization and planning

Effectively communicate plans and results in both oral and written form

Ability to work in a highly dynamic collaborative team environment

Other duties as assigned

QUALIFICATIONS AND EXPERIENCE


BS or MS degree in immunology/cell biology

0 – 5+ years of experience in the immunology/immunotherapy field (immunotherapy background strongly preferred)

Excellent mammalian cell culture and sterile technique required

Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo) required

Experience with immune cell-based assays including cytotoxicity assays, cell proliferation assays and ELISAs

Experience with viral and/or non-viral gene delivery

Proficiency in Excel, PowerPoint, Prism, and other programs to create and distribute reports

Excellent problem-solving and time management skills

Strong organizational and record keeping skills

Self-motivated and willing to accept temporary responsibilities outside of job description

Comfortable in a fast-paced company and able to adjust workload based upon changing priorities

Excellent interpersonal, verbal and written communication skills with the ability to interact with individuals from a variety of levels and functions


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