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Sr.Research Associate, Flow Cytometry and Cell Line Development Core

Emeryville, CA, USA | Leading Pharmaceutical / Biotech Company

  • Industry:
    Pharmaceutical / Biotech
  • Position Type:
    Full-Time
  • Functions:
    Biotech/R&D/Science
  • Experience:
    5-7 years
Job Description:
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Job Description


We are seeking an experienced, creative and motivated Senior Research Associate or a Research Associate to join our growing team in Emeryville.In this role, you will contribute to the company’s efforts to develop next-generation cell therapies in solid tumor malignancies.The successful candidate will have a strong Flow Cytometry background and Cell Line Development Core experience and will be expected to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.




 


DUTIES AND RESPONSIBILITIES:


Seeking a highly motivated individual who shares the enthusiasm for flow cytometry, Automation, CRISPR engineering, Cell biology and loves to learn; general responsibilities include but are not limited to;


Cell line establishment using cutting edge techniques; CRISPR, antibiotic selections, viral, non-viral methods and electroporation


Create, characterize, and maintain novel target and reporter cell lines. Develop and Implement automation in CAR T assays


Perform daily instrument QC, maintain and troubleshoot Flow cytometry instruments


Perform cell sorting on SONY and Fusion cell sorters.


Evaluate new Cytometry technology (Software and Hardware) and stay current on literature relevant to flow cytometry keeping the lab current and upto date.


Test and develop new multicolor panels for T cell Collect, organize, interpret, and present data in small and large group meetings.


Contribute to a dynamic, exciting culture that embraces teamwork and innovation.


 


EDUCATION AND EXPERIENCE:


B.S. degree with 4-6+ years of experience, M.S. degree with 2-4 years of experience


Degree in biology-related field required; degree in molecular biology, immunology or cell biology highly preferred


Prior experience in flow cytometry instruments, cell sorting preferred and experience in automation desired


Experience with mammalian cell culture


PREFERRED TECHNICAL SKILLS:


Knowledge in Molecular biology techniques, CRISPR editing, Lenti-viral transduction


Knowledge of flow cytometry.


Single cell sorting


Experience with panel design, compensation, data analysis using FlowJo or other software


Proficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad


Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook)


Proliferation and cytotoxicity assays


Proven ability to work and think independently and creatively; be an affable and energetic colleague and team player


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